研究業績

2022

  • (This article is a preprint and has not been certified by peer review)
    Arihisa W., Kondo T., Yamaguchi K., Matsumoto J., Nakanishi H., Kunii Y., Akatsu H., Hino M., Hashizume Y., Sato S., Sato S., Niwa S., Yabe H., Sasaki T., Shigenobu S., Setou M.
    Lipid-correlated alterations in the transcriptome are enriched in several specific pathways in the postmortem prefrontal cortex of Japanese patients with schizophrenia.
    bioRxiv, 2022.03.14.483348
    https://doi.org/10.1101/2022.03.14.483348
  • Sugisawa E.#, Kondo T.#, Kumagai Y., Kato H., Takayama Y., Isohashi K., Shimosegawa E.,  Takemura N., Hayashi Y., Sasaki T., Martino M.M., Tominaga M., & Maruyama K.* 
    Nociceptor-derived Reg3g prevents endotoxic death by targeting kynurenine pathway in microglia.
    Cell Reports, 38(10), 110462, 2022.
    https://doi.org/10.1016/j.celrep.2022.110462
    #These authors contributed equally *Corresponding author

  • Hino, M., Kondo, T., Kunii, Y., Matsumoto, J., Wada, A., Niwa, S. I., Setou, M., & Yabe, H.
    Tubulin/microtubules as novel clozapine targets.
    Neuropsychopharmacology reports, 42(1), 32-41. 2022.
    https://doi.org/10.1002/npr2.12221

2021

  • Nakazono, A., Nakamaru, Y., Ramezanpour, M., Kondo, T., Watanabe, M., Hatakeyama, S., Kimura, S., Honma, A., Wormald, P. J., Vreugde, S., Suzuki, M., & Homma, A.
    Fluticasone Propionate Suppresses Poly(I:C)-Induced ACE2 in Primary Human Nasal Epithelial Cells.
    Frontiers in cellular and infection microbiology, 11, 655666. 2021.
    https://doi.org/10.3389/fcimb.2021.655666

2020

  • Watanabe, M., Saeki, Y., Takahashi, H., Ohtake, F., Yoshida, Y., Kasuga, Y., Kondo, T., Yaguchi, H., Suzuki, M., Ishida, H., Tanaka, K., & Hatakeyama, S.
    A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets.
    Communications biology, 3(1), 592. 2020.
    https://doi.org/10.1038/s42003-020-01328-y
  • Maruyama, K., Kidoya, H., Takemura, N., Sugisawa, E., Takeuchi, O., Kondo, T., Eid, M., Tanaka, H., Martino, M. M., Takakura, N., Takayama, Y., Akira, S., Vandenbon, A., & Kumagai, Y.
    Zinc Finger Protein St18 Protects against Septic Death by Inhibiting VEGF-A from Macrophages.
    Cell reports, 32(2), 107906. 2020.
    https://doi.org/10.1016/j.celrep.2020.107906.
  • Sugisawa, E.#, Takayama, Y.#, Takemura, N.#, Kondo, T.#, Hatakeyama, S., Kumagai, Y., Sunagawa, M., Tominaga, M., & Maruyama, K.*.
    RNA Sensing by Gut Piezo1 Is Essential for Systemic Serotonin Synthesis.
    Cell. 182(3), 609–624.e21. 2020.
    https://doi.org/10.1016/j.cell.2020.06.022
    #These authors contributed equally *Corresponding author

2019

  • Sato, T., Horikawa, M., Takei, S., Yamazaki, F., Ito, T. K., Kondo, T., Sakurai, T., Kahyo, T., Ikegami, K., Sato, S., Sato, R., Jinno, Y., Kawano, H., Naoe, S., Arita, M., Kashiwagi, Y., & Setou, M.
    Preferential Incorporation of Administered Eicosapentaenoic Acid Into Thin-Cap Atherosclerotic Plaques.
    Arteriosclerosis, thrombosis, and vascular biology, 39(9), 1802–1816. 2019.
    https://doi.org/10.1161/ATVBAHA.119.313093

2018

  • Maruyama K, Takayama Y, Sugisawa E, Yamanoi Y, Yokawa T, Kondo T, Ishibashi KI, Sahoo BR, Takemura N, Mori Y, Kanemaru H, Kumagai Y, Martino MM, Yoshioka Y, Nishijo H, Tanaka H, Sasaki A, Ohno N, Iwakura Y, Moriyama Y, Nomura M, Akira S, Tominaga M.
    The ATP Transporter VNUT Mediates Induction of Dectin-1-Triggered Candida Nociception.
    iScience, 6, 306-318. 2018.
  • Sato S, Horikawa M, Kondo T, Sato T, Setou M.
    A power law distribution of metabolite abundance levels in mice regardless of the time and spatial scale of analysis.
    Sci Rep., 8(1), 10315. 2018.

2017

  • Maruyama K, Takemura N, Martino MM, Kondo T, Akira S.
    Netrins as prophylactic targets in skeletal diseases: A double-edged sword?
    Pharmacol Res., 122, 46-52. 2017.
  • Maruyama K, Takayama Y, Kondo T, Ishibashi KI, Sahoo BR, Kanemaru H, Kumagai Y, Martino MM, Tanaka H, Ohno N, Iwakura Y, Takemura N, Tominaga M, Akira S.
    Nociceptors Boost the Resolution of Fungal Osteoinflammation via the TRP Channel-CGRP-Jdp2 Axis.
    Cell Rep., 19(13), 2730-2742. 2017.
  • Matsumoto J, Nakanishi H, Kunii Y, Sugiura Y, Yuki D, Wada A, Hino M, Niwa SI, Kondo T, Waki M, Hayasaka T, Masaki N, Akatsu H, Hashizume Y, Yamamoto S, Sato S, Sasaki T, Setou M, Yabe H.
    Decreased 16: 0/20: 4-phosphatidylinositol level in the post-mortem prefrontal cortex of elderly patients with schizophrenia.
    Sci Rep., 7, 45050. 2017.
  • Hirayama-Kurogi M, Takizawa Y, Kunii Y, Matsumoto J, Wada A, Hino M, Akatsu H, Hashizume Y, Yamamoto S, Kondo T, Ito S, Tachikawa M, Niwa SI, Yabe H, Terasaki T, Setou M, Ohtsuki S. Downregulation of GNA13-ERK network in prefrontal cortex of schizophrenia brain identified by combined focused and targeted quantitative proteomics.
    J Proteomics, 158, 31-42. 2017.

2016

  • Maruyama K, Kawasaki T, Hamaguchi M, Hashimoto M, Furu M, Ito H, Fujii T, Takemura N, Karuppuchamy T, Kondo T, Kawasaki T, Fukasaka M, Misawa T, Saitoh T, Suzuki Y, Martino MM, Kumagai Y, Akira S.
    Bone-protective Functions of Netrin 1 Protein.
    J Biol Chem., 291(46), 23854-23868. 2016.

2015

  • Maruyama K, Fukasaka M, Uematsu S, Takeuchi O, Kondo T, Saitoh T, Martino MM, Akira S.
    5-Azacytidine-induced protein 2 (AZI2) regulates bone mass by fine-tuning osteoclast survival.
    J Biol Chem., 290(15), 9377-9386. 2015.
  • Waki M, Sugiyama E, Kondo T, Sano K, Setou M.
    Nanoparticle-assisted laser desorption/ionization for metabolite imaging.
    Methods Mol Biol., 1203, 159-173. 2015.

2014

  • Waki M, Ide Y, Ishizaki I, Nagata Y, Masaki N, Sugiyama E, Kurabe N, Nicolaescu D, Yamazaki F, Hayasaka T, Ikegami K, Kondo T, Shibata K, Hiraide T, Taki Y, Ogura H, Shiiya N, Sanada N, Setou M.
    Single-cell time-of-flight secondary ion mass spectrometry reveals that human breast cancer stem cells have significantly lower content of palmitoleic acid compared to their counterpart non-stem cancer cells.
    Biochimie, 107, 73-77. 2014.
  • Ide Y, Waki M, Ishizaki I, Nagata Y, Yamazaki F, Hayasaka T, Masaki N, Ikegami K, Kondo T, Shibata K, Ogura H, Sanada N, Setou M.
    Single Cell Lipidomics of SKBR-3 Breast Cancer Cells by Using Time-of-Flight Secondary-Ion Mass Spectrometry.
    Surf Interface Anal., 46(S1), 181-184. 2014.

2013

  • Maruyama K, Uematsu S, Kondo T, Takeuchi O, Martino MM, Kawasaki T, Akira S.
    Strawberry notch homologue 2 regulates osteoclast fusion by enhancing the expression of DC-STAMP.
    J Exp Med., 210(10), 1947-1960. 2013.
  • Kondo T, Kobayashi J, Saitoh T, Maruyama K, Ishii KJ, Barber GN, Komatsu K, Akira S, Kawai T.
    DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking.
    Proc Natl Acad Sci U S A., 110(8), 2969-2974. 2013.

2012

  • Maruyama K, Fukasaka M, Vandenbon A, Saitoh T, Kawasaki T, Kondo T, Yokoyama KK, Kidoya H, Takakura N, Standley D, Takeuchi O, Akira S.
    The transcription factor Jdp2 controls bone homeostasis and antibacterial immunity by regulating osteoclast and neutrophil differentiation.
    Immunity, 37(6), 1024-1036. 2012.
  • Kondo T, Kawai T, Akira S.
    Dissecting negative regulation of Toll-like receptor signaling.
    Trends Immunol., 33(9), 449-458. 2012.
  • Maruyama K, Kawagoe T, Kondo T, Akira S, Takeuchi O.
    TRAF family member-associated NF-κB activator (TANK) is a negative regulator of osteoclastogenesis and bone formation.
    J Biol Chem., 287(34), 29114-29124. 2012.
  • Kondo T, Watanabe M, Hatakeyama S.
    TRIM59 interacts with ECSIT and negatively regulates NF-κB and IRF-3/7-mediated signal pathways.
    Biochem Biophys Res Commun., 422(3), 501-507. 2012.